Neurology Today in 5 cover

Neurology Today in 5

American Academy of Neurology

Joseph E. Safdieh, MD, FAAN, Editor-in-Chief of Neurology Today highlights the most noteworthy and newsworthy neurology stories in the issue.

Joseph E. Safdieh, MD, FAAN, Editor-in-Chief of Neurology Today highlights the most noteworthy and newsworthy neurology stories in the issue.

Lamotrigine in Pregnancy, Professional Mentorship, CADASIL Misdiagnosis

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Lamotrigine in Pregnancy, Professional Mentorship, CADASIL Misdiagnosis 15 Oct 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the use of lamotrigine during pregnancy, the value of professional mentorship, and the misdiagnosis of CADASIL as multiple sclerosis.

Wearable Devices, Thrombectomy Debate, Muscular Dystrophy Therapy 01 Oct 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the pros and cons of wearable devices, new data for thrombectomy use in medium-vessel occlusion strokes, and a new treatment for limb-girdle muscular dystrophy type 2I/R9.

Oral PCSK9 Inhibitor, Role of Neurology Department Chairs, Anti-IgLON5 Disease 17 Sep 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the first oral PCSK9 inhibitor, the transforming role of the neurology department chair, and anti-IgLON5 disease.

New Migraine Prevention Guidelines, Plasmapheresis for MOGAD Attacks, Benefits of Sabbaticals 03 Sep 2026

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about new migraine prevention guidelines, the use of plasmapheresis for acute MOGAD attacks, and how sabbaticals can help neurologists avoid burnout.

'One Big Beautiful Bill Act' Impact, Artificial Intelligence and Workload, GBA1 Mutations in Parkinson's Disease 20 Aug 2026

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about the impact of the "One Big Beautiful Bill Act" on neurology practice and research, how artificial intelligence is transforming the neurologist's workload, and the relationship between GBA1 mutations and Parkinson's disease.

American Board of Psychiatry and Neurology Academic Pathway, EpiWatch App, Multiplexed MR Scanning 06 Aug 2026

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about a pilot American Board of Psychiatry and Neurology Academic Pathway, a study of the EpiWatch app, and a new approach to magnetic resonance scanning.

Cognitive Decline Biomarker, Tirofiban's Impact on Stroke, Peer Reviewers' Use of Artificial Intelligence 16 Jul 2026

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about a blood test that could predict cognitive decline before pathological signs, the use of tirofiban after tenecteplase for stroke, and the role of artificial intelligence in peer review.

OCEANIC-STROKE Study Results, High-Dose Flu Vaccine and Alzheimer's Risk, Role of Osteopathic Medicine in Neurology 02 Jul 2026

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about asundexian reducing recurrent ischemic stroke, the link between the high-dose flu vaccine and Alzheimer's dementia incidence, and the evolving role of osteopathic medicine in neurology.

Wait Times for New Neurology Visits, Post-Traumatic Headache Severity in Children, New Drug for Alzheimer's Agitation 18 Jun 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about appointment wait times for commercially insured patients, post-traumatic headache severity in children with a family history of migraine, and the FDA approval of a drug for Alzheimer's agitation.

Meat Intake and Cognitive Decline, Geographic Distribution of Research Funding, Artificial Intelligence's Role in Neurology 04 Jun 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about a link between higher meat and slower cognitive decline in APOE34/44 carriers, the geographic distribution of research funding, and how artificial intelligence is reshaping neurology.

New Dopamine Agonist for Parkinson's, Artificial Intelligence in Medical Journals, Coffee and Dementia Risk 21 May 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about a new selective dopamine agonist for people with Parkinson's disease, the use of artificial intelligence in preparing journal manuscripts, and caffeinated coffee's role in reducing dementia risk.

Neurology Match Day Growth, Diabetes and Dementia Risk, Public Health Discourse 07 May 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the increase in neurology residency matches this year, the risk of dementia in people with Type 1 diabetes, and the role of neurologists in the public health conversation.

Academic Jobs for Fellowship Graduates, Complex Neuromuscular Treatments, New Stroke Guideline 16 Apr 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the academic job market for fellowship graduates, the challenges of today's complex neuromuscular therapies, and the changes made in a new stroke guideline.

Acetaminophen Use During Pregnancy, Air Pollution and Motor Neuron Disease, Fremanezumab for Pediatric Migraine 02 Apr 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about acetaminophen use during pregnancy, the link between air pollution and motor neuron disease risk, and the use of fremanezumab for pediatric migraine.

ACGME neurocritical care accreditation, Jamaica hurricane aftermath, rituximab for multiple sclerosis 19 Mar 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about ACGME neurocritical care accreditation, how neurologists in Jamaica are recovering from hurricane damage, and the use of rituximab maintenance dosing in multiple sclerosis.

West Nile Neuroinvasive Disease, NINDS Director's Departure, Advanced Practice Provider Educational Funding 05 Mar 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about West Nile neuroinvasive disease, what's next after NINDS director Dr. Walter Koroshetz's departure, and changes to funding for advanced practice providers' education.

EMG Expertise, GLP-1s and Epilepsy, Astrocytoma Combination Therapy 19 Feb 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about EMG expertise, GLP-1s and epilepsy risk reduction, and combination therapy for recurrent IDH-mutant astrocytoma.

EMG Expertise, GLP-1s and Epilepsy, Astrocytoma Combination Therapy 19 Feb 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about EMG expertise, GLP-1s and epilepsy risk reduction, and combination therapy for recurrent IDH-mutant astrocytoma.

Lasmiditan Discontinuation, DAAN Designation, Alteplase for Eye Stroke 05 Feb 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the discontinuation of lasmiditan, the new DAAN designation, and the use of alteplase after eye stroke.

Genetic Counselors, Wrist-Worn Stimulation Device for Essential Tremor, CREST-2 Study Results 15 Jan 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the growing role of genetic counselors in neurology, a wrist-worn stimulation device for essential tremor, and results from the CREST-2 study of asymptomatic carotid disease.

Shunt Benefit in iNPH, Downstream Revenue, Anticoagulant Monotherapy 02 Jan 2026

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the benefit of shunts in idiopathic normal-pressure hydrocephalus, how neurologists drive downstream revenue, and anticoagulant monotherapy after stroke.

P-tau217 Alzheimer's Blood Test, Tirofiban With Thrombolysis, Artificial Intelligence in Diagnostic Coding 18 Dec 2025

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about a p-tau217 blood test for Alzheimer's disease, the benefits of tirofiban with thrombolysis, and an AI tool that excels in diagnostic coding.

Medical school acceptance, hemorrhagic stroke surgery, brain tumors after TBI 04 Dec 2025

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about medical school acceptance rates after the ending of affirmative action, minimally invasive surgery for hemorrhagic stroke, and the increased risk of brain tumors after traumatic brain injury.

Artificial sweeteners cognition concerns, drug company payments and prescribing decisions, graphene technology 20 Nov 2025

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about artificial sweeteners' impact on cognitive health, how drug company payments influence prescribing decisions, and the use of graphene technology to accelerate maturation of neurons.

50 years of monoclonal antibodies, pregabalin and heart failure, combined therapy for primary progressive aphasia 06 Nov 2025

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about how monoclonal antibodies revolutionized neurologic treatment, why pregabalin link to increased heart failure, and a combined therapy that slows progression in primary progressive aphasia.

Novel PET radiotracer, GLP-1s and dementia risk, green space benefits 16 Oct 2025

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about a PET radiotracer that shows intranasally delivered insulin enters the brain, GLP-1s and dementia risk in people with Type 2 diabetes, and how exposure to green space may reduce the risk of neurodevelopmental delays in children.

Pegivirus' role in Parkinson's disease, GLP-1s and idiopathic intracranial hypertension, geographic spread of epilepsy specialists 02 Oct 2025

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about pegivirus's potential role in Parkinson's disease pathology, the impact of GLP-1 receptor agonistst on idiopathic intracranial hypertension, and the geographic spread of epilepsy specialists.

Food deserts and stroke risk, physical activity in Parkinson's disease, rimegepant for migraine 18 Sep 2025

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the relationship between income, "food deserts," and stroke risk; why staying active may reduce cognitive decline in patients with Parkinson's disease; and how initiating rimegepant for migraine could help reduce opioid and butalbital use.

Parkinson's and dementia with Lewy bodies blood test, CAR T-cell therapy for glioblastoma, wireless EEG 04 Sep 2025

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about a promising blood test to distinguish Parkinson's disease from dementia with Lewy bodies, how CAR T-cell therapies are showing potential for patients with glioblastoma, and a new wireless electroencephalogram device that can even monitor young children with epilepsy.

Small fiber neuropathy, Dr. Merit Cudkowicz, work-life balance for families of neurologists 21 Aug 2025

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about whether small fiber neuropathy is an autoimmune disorder; Merit Cudkowicz, MD, MSc, FAAN, recipient of this year's AAN Lifetime Achievement Award for Clinically Relevant Research; and how neurologist couples pursue work-life balance.

Divisive treatment for cluster headache, head positioning before thrombectomy, new series, "Neurology in America" 07 Aug 2025

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about eptinezumab, a treatment for episodic cluster headache; how positioning the head flat before a thrombectomy benefited patients with large vessel occlusion stroke; and what rural neurology looks like in 2025, the first story in our new series, Neurology in America.

New treatment for giant-cell arteritis, links between oral and brain health, an emerging meningitis B vaccine 17 Jul 2025

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about upadacitinib, a new treatment for giant-cell arteritis; growing evidence linking oral health to a higher risk of neurologic conditions; and why a trial of a new meningitis B vaccine drew a mixed response.

Telomere length and and risk for neurologic disorders, impact of research cuts on promotion/tenure, herpes zoster vaccine and dementia 03 Jul 2025

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles on the association of shortened telomeres on risk for stroke, late-life depression and dementia; affect of research funding cuts on tenure/promotion opportunities; and herpes zoster vaccine and reduced dementia risk.

Post-TIA fatigue, neurologic complications of measles, CDC surveillance of epilepsy program dismantled. 19 Jun 2025

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles studies showing persistent fatigue after TIA, the neurologic complications of measles, and the impact of the dismantling of a CDC surveillance program of epilepsy.

Post-TIA fatigue, neurologic complications of measles, CDC surveillance of epilepsy program dismantled. 05 Jun 2025

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles studies showing persistent fatigue after TIA, the neurologic complications of measles, and the impact of the dismantling of a CDC surveillance program of epilepsy.

Advances in cell therapies for Parkinson's, GLP-1 agonists and dementia risk, FDA accelerated approvals for neurology drugs 15 May 2025

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about early studies finding dopamine cellular therapies were safe and tolerable for patients with Parkinson's, use of GLP-1 agonists were associated with reduced dementia risks, and the FDA use of accelerated approvals for several neurology drugs are under scrutiny.

Microplastics in brain, salary gap in neurology, the neurology of space 01 May 2025

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles finding microplastics in the brain postmortem linked to dementia, the salary gap between men and women neurologies, and neurologists studying the impact of microgravity on the brain.

Impact of high-dose Vitamin D on MS relapse, the role of AI in neurology education, and a 4D animal model that shows precursors of MS lesions before they appear. 17 Apr 2025

In this episodeof Neurology Today in 5, Neurology Today editor-in-chief Joseph E. Safdieh, MD, FAAN, discusses a large trial that found high-dose Vitamin D reduced MRI evidence of disease activity in patients with clinically isolated syndrome or early relapsing MS; an animal brain map, revealing changes in inflammation, immune activity, and cell repair that preceded the appearance of MS lesions; and a discussion of the challenges and opportunities of using AI in neurology education.

New approved drug for neurofibromatosis 1 with plexiform neurofibromas, multidisciplinary clinics in neurology, impact of cuts to DEI research grants 03 Apr 2025

In this week's podcast, Neurology Today's editor-in-chief highlights articles on the newly approved drug for neurofibromatosis 1 with plexiform neuromas in adults, how neurology practices are integrating with multiple subspecialties, and the impact of federal cuts to DEI grants and research.

Impact of NIH cuts on neurology research, response to ACP's guideline on migraine, an updated position on seizures, driver licensure, and medical reporting 20 Mar 2025

In this week's podcast, Neurology Today's editor-in-chief highlights articles on the impact of NIH cuts to indirect research costs, response to a new guideline on migraine prevention from ACP, and an updated position statement from the AAN on seizures, driver licensures, and medical reporting.

Lifetime burden of dementia, hidden features on EEGs for epilepsy detection, neurology-trained pharmacists 06 Mar 2025

In this week's podcast, Neurology Today's editor-in-chief highlights articles on the larger lifetime burden of dementia than projected, an AI-fueled program that detects hidden features in EEGs for epilepsy detection, and neurology-trained pharmacists who are working with neurology departments.

IVF and MS relapse, community-based neurologists doing clinical research, and the loneliness protein implicated in brain function. 20 Feb 2025

In this week's podcast, Neurology Today's editor-in-chief highlights articles on new data on IVF safety for women with MS, an elevated protein associated with loneliness, social isolation and brain function, and the role of community-based neurologists in drug development.

Remote neurology education, tirzepatide for obesity-related OSA, artificial intelligence for glioma assessment 06 Feb 2025

In this week's podcast, Neurology Today's editor-in-chief highlights articles on the pros and cons of virtual neurology education, the FDA approval of tirzepatide for obesity-related obstructive sleep apnea, and the promise of AI for glioma assessment.

Middle meningeal artery embolization and subdural hematoma, processed red meat and dementia risk, and editor picks for best neurology advances of 2024. 16 Jan 2025

In this week's podcast, Neurology Today's editor-in-chief highlights articles on the safety of middle meningeal artery embolization for chronic subdural hematoma, the processed red meat and risk for dementia, and editors' picks for the best advances of 2024.

Magnesium sulfate for cerebral palsy, novel gene therapy for muscular dystrophies, chronic traumatic encephalitis and suicidality in retired NFL players. 02 Jan 2025

In this week's podcast, Neurology Today's editor-in-chief highlights articles on the latest Cochrane review of magnesium sulfate to prevent cerebral palsy; a novel mRNA system for gene therapy for muscular dystrophies, and the perception of CTE and suicidality risk in retired NFL players.

Revised criteria for diagnosing MS, AI for alleviating administrative burden, neonatal neurocritical care as a growing subspecialty 19 Dec 2024

In this week's podcast, Neurology Today's editor-in-chief highlights articles on proposed updated criteria for diagnosing MS before symptoms manifest, the use of large language models to address administrative burden with electronic medical records, and the growth of training programs in neonatal neurocritical care.

3-year outcomes for anti-NMDAR encephalitis, skin biopsies for diagnosis of human prion diseases, the career benefits of graduate degrees in public health and/or business administration 05 Dec 2024

In this week's podcast, Neurology Today's editor-in-chief highlights articles on a study highlighting three-year outcomes for patients with anti-NMDAR encephalitis, an analysis comparing the diagnostic efficacy of skin biopsies vs. CSF tests for human prion diseases, and the ways in which a graduate degree in public health and/or business administration can shape career pathways for neurologists.

Cardiovascular effects of antiseizure therapies, social determinants of health on children with MS, coverage for blood-based biomarkers for Alzheimer's 21 Nov 2024

In this week's podcast, Neurology Today's editor-in-chief highlights articles on the higher risk for cardiovascular effects with certain antiseizure therapies on adults with epilepsy, the impact of social determinants of health on children with MS, and the status of coverage for blood-based tests for Alzheimer's disease.

Fever prevention and stroke, environmental toxins and Parkinson's, cholesterol overload and ALS progression 07 Nov 2024

In this week's podcast, Neurology Today's editor-in-chief highlights articles on fever prevention and stroke outcomes, the impact of air pollution and other environmental toxins on Parkinson's, and the role of cholesterol overload in ALS progression and disease risk.

Blood test for ALS, new migraine target reduces headache days, latest data on eculizumab for neuromyelitis optica spectrum disorder 17 Oct 2024

In this week's podcast, Neurology Today's editor-in-chief highlights articles on the potential of a new blood biomarker for ALS, a PACP-targeted migraine therapy, and a real-world review of data on eculizumab for neuromyelitis optica spectrum disorder. This Podcast is being Sponsored by LocumTenens.com

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